Type 2 diabetes can be prevented

bikezappa

http://www.msnbc.msn.com/id/24790626/

This is another in many studies that we pay for. The conclusion is that if you exercise and eat less sugar you will dramtically reduce the risk of getting Type 2 diabetes. What concerns me is that this fact was know since WWII. The incidence of new Type 2 diabetics in England during WWII almost went to zero. The simple conclusion was that people in England ate less and exercised more during the war. After the war ended the incidence of Type II returned to normal.

I have had Type I diabetes for 50 years and have been very lucky. I ride to work on my bike as much as possible and try to control my food intake.

The real question is why don't people exercise and over eat?

Also why do they continue with these studies?

Ricardo

bikezappa wrote: »

The real question is why don't people exercise and over eat?

Because we are lazy and love food?

Shizelbs

I'm certain that the endpoints of the study were a touch more complex and involved than 'does modifying one's caloric balance prevent diabetes'.

bikezappa

After a short stay in America David returns to Europe.

bikezappa

"Diabetes can be delayed with a few simple fixes"
is the headline of the article.

Shizelbs

bikezappa wrote: »

"Diabetes can be delayed with a few simple fixes"
is the headline of the article.

That may be. Popular media is far from perfect at accurately reporting findings from medical studies.

fossy

The drug companies gonna come calling on ya -- they don't like news like this :eek::eek:-- but you are absolutely right -- Majority of us here in America eat to much & eat all the wrong stuff -- I am one of them but lately I have been tryin to eat better & get a little exercise, even if it's a simple walk around the block-- My mother has had both legs amputated because of diabetes so it is always on my mind

bikezappa

fossy wrote: »

The drug companies gonna come calling on ya -- they don't like news like this :eek::eek:-- but you are absolutely right -- Majority of us here in America eat to much & eat all the wrong stuff -- I am one of them but lately I have been tryin to eat better & get a little exercise, even if it's a simple walk around the block-- My mother has had both legs amputated because of diabetes so it is always on my mind

Along with blindness and kidney failure.

petrym

I have a friend in my quartet that has Type 2, he's in the process of losing weight and is scaling back the meds to match.

Now I have to lose some stockpiled DNA...

ShinAce

bikezappa wrote: »

Along with blindness and kidney failure.

Let's not forget heart complications and even strokes.

Shizelbs

What about depression and increased rates of divorce?

Demiurge

PharmD: 2

Beatnicks: 0

bikezappa

It's the remotes fault.
Throw away the remotes, get out of the chair and start moving more.

Early B.

I've witnessed firsthand Type II diabetes being totally reversed with diet alone.

Shizelbs

What's their A1c?

Demiurge

Demiurge wrote: »

PharmD: 3

Beatnicks: 0

It's a blowout folks.

WilliamM2

bikezappa wrote: »

It's the remotes fault.
Throw away the remotes, get out of the chair and start moving more.

But then I would get fingerprints on the equipment.:eek:

fossy

Early B. wrote: »

I've witnessed firsthand Type II diabetes being totally reversed with diet alone.

tell more please I would just guess eliminating dairy products,salt & any processed food ????

Deadof_knight

whole foods and exercise ... its that simple....I wanna live long enough so my grand kids come in an go grandpa turn it dow !

Shizelbs

Salt doesn't have a great deal to do with developing diabetes.

Early B.

fossy wrote: »

tell more please I would just guess eliminating dairy products,salt & any processed food ????

Exactly. We placed one of our former elderly clients who had been released into hospice care on a vegetarian diet and weened her totally off insulin, and regulated her blood sugar with diet. She lived for a couple more years thereafter. The hospice nurses were flabbergasted.

Airplay355

you generally don't give type 2 diabetics insulin as there is no problem with their pancreas. Type 1 diabetes is thought to be an autoimmune disease in which the cells in the pancreas which create insulin are killed. Type 2 diabetes is insulin resistance so normal levels of insulin are produced however insulin receptors don't respond as well to insulin. You could give them insulin to increase the chance of insulin binding to a receptor but diet and exercise is a better treatment option for type 2 diabetes.

Shizelbs

You generally don't give Type 2s insulin initially because giving yourself shots and poking your finger for blood sucks. In general you stick with oral meds as long as possible until those are no longer effective enough. Insulin is a great treatment option, however, for Type 2s that can benefit from it. Eventually, with enough time and resistance, in type 2s, the pancreas calls it quits as well, its just not due to an immune response.

Airplay355

You don't have to give yourself shots. There's subcutaneous insulin. And poking your finger isn't fun but it's not horrible. Overall the best option is to lose some lbs.

bikezappa

Shizelbs wrote: »

You generally don't give Type 2s insulin initially because giving yourself shots and poking your finger for blood sucks.

The article says that sometimes giving type 2s insulin first allows the pancreas to rest and recover. If the pancreas is working you can get excellent blood sugar control and avoid all the diabetic complications. I think these type 2s take the long lasting insulin once per day to.

This makes sense because the pills try to rejuvinate the pancreas, but it will eventually failure unless the livestyle changes.

I think but have no data to prove it but I think exercise helps the body utilize insulin much better. This has been my presonnel experience. If I exercise I need much less insulin each day.

Airplay355

Insulin tells cells in the body to absorb glucose in the blood so maybe by exercising you're depleting the large glycogen stores in your liver and muscles. You're liver will absorb glucose from your blood regardless of the levels of insulin in your blood so if you're depleting energy stores there it will absorb more glucose from your blood to replenish glycogen stores thus lowering you're blood sugar and allowing you to use less insulin.

I just made that up now but it seems plausible to me.

PS the pancreas doesn't pack up and quit in type 2 diabetics it fails because it's going to attempt to overproduce insulin at first to compensate for the insulin resistance. If it's forced into overproduction for a long time it will fail. Giving artificial insulin to type two diabetics would raise insulin levels (which is what the pancreas is naturally trying to do) in order to hopefully give the pancreas a break. The reason your body wants to increase insulin production is because with higher concentrations of insulin there is more of a chance the hormone will bind to a receptor and cause it's effects, in this case glucose absorption.

bikezappa

I'm no expert but as I understand it the insulin reacts with the glucose in the blood to break down it's size so it can pass throught the cell membrane. The broken down glucose can now leave the blood, pass throught the cell membrane and feed the cell. If you don't have enough insulin in the blood your blood will start to have more and more glucose in it because it can't pass through the cell membrane. That's called high blood sugar that we can measure now with meters and a drop of blood. Your body hates to have high blood sugar so it gets rid of it with the kidneys and you need to piss. That's why one of the symptoms of diabetes is lots of pissing. Over time your kidneys will fail trying to remove all the glucose in your blood.

A second result of not enough insulin in the blood is that inorder to feed your cells they will eat the fat stored if the cells have no glucose. What this means is that you can eat anything, digest it, pass this food to your blood then kidneys and you will start to lose weight. Diabetics before insulin would get very thin and die. The test for diabetics way back then was for the doctor to taste your pee, if it tasted sweet you had diabetes and would die in a few months.

When they first tried insulin, the diabetic would recover in a short time but relapse if not given more insulin.

Airplay355

Insulin is actually a hormone. It controls the absorption of glucose into cells except cells in the brain, kidneys and liver which will uptake glucose regardless of the amounts of insulin present. Without insulin, cells in the body do not absorb glucose so blood glucose levels remain high. Glucose is as simple of a sugar as you can get, the body will use glucose directly and does not break it down into a smaller molecule but will store it in larger molecules like glycogen.

The reason diabetics piss so much is because the large amounts of glucose are removed in the kidneys. Large amounts of glucose in kidney tubules osmotically draws water from the blood stream resulting in large quantities of sugary piss called osmotic diuresis. Diabetes mellitus literally means sweet flow because back in the day if your piss was sweet you had diabetes. A person with normal hormonal control will never piss glucose as it will always be reabsorbed and store in one form or another. The reason diabetics piss glucose is because there are certain channels in kidney tubules responsible for the resorption of glucose. Without proper hormonal control diabetics can have crazy high blood sugars, even in the thousands of mg/deciliter. WHen your blood sugar gets that high it is possible to saturate the carrier channels and then some glucose will pass by the portion of the tubule with glucose channels and the glucose will end up in the urine. Normal blood glucose is between 70 and 140 mg/dl and a normal person uses two hormones to regulate this, insulin which causes glucose uptake from the blood, and glucagon which causes the liver to break down glycogen (a molecule which is a bunch of glucoses strung together) and release it into the blood in order to raise blood sugar. Low blood sugar is worse then high blood sugar as it will send you into a diabetic coma, thats why it's a good idea to keep some M&Ms around or a glucagon shot around just in case you accidentally end up with extremely low blood sugar.

Cells don't eat fat. There's no portion of cellular respiration in which cells use any type of lipid molecule as fuel. Glycolosis is where cells get energy from and it's from the breakdown of glucose.

Shizelbs

Airplay355 wrote: »

Insulin tells cells in the body to absorb glucose in the blood so maybe by exercising you're depleting the large glycogen stores in your liver and muscles. You're liver will absorb glucose from your blood regardless of the levels of insulin in your blood so if you're depleting energy stores there it will absorb more glucose from your blood to replenish glycogen stores thus lowering you're blood sugar and allowing you to use less insulin.

You are correct sir.

Shizelbs

bikezappa wrote: »

This makes sense because the pills try to rejuvinate the pancreas, but it will eventually failure unless the livestyle changes.

Oral meds do the following; decrease absorption of sugars from the GI tract, enhance hepatic uptake of glucose, enhance uptake of glucose by the muscles, stimulate the pancreas to release more insulin, make insulin receptors more sensitive. I'm sure I'm missing something, but these are the main possible effects of oral diabetes meds.

bikezappa

Airplay355 wrote: »

Glucose is actually a hormone. It controls the absorption of glucose into cells except cells in the brain,

Glucose (Glc), a monosaccharide (or simple sugar), is an important carbohydrate in biology.

I never heard anyone call glucose a hormone. I think you meant to thay that insulin is a hormone. And that is dead on.