Can I use PSW111 with RM 5000/RM3000 setup?

I currently have the following speaker setup: RM5000 w/passive sub for my front and center speakers and RM3000 w/passive sub for my rear speakers. I am looking at adding a PSW111 powered subwoofer to the system. It would be connected to the LFE sub out connection on my receiver which is Dolby Digital.

First off can I use the PSW111 sub with my current set up with 2 passive subs?
If the answer is yes what would be the receiver settings I would need to use for the speakers and sub?