Tweaking a new setup

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Greetings and thanks in advance for your shared knowledge.
I own a Yamaha AV receiver RX-V679 and am using it in a 2.1 format with two Elac B6 Debut speakers and a PSW-505 sub. I may add additional speakers in the future but my current focus is to get the best settings for both listening to music and viewing movies.
I am not sure which connection method or settings are best for the sub with this 2.1 configuration.
R. Cox
Florida
"When the going gets weird, the weird turn pro."